Serotonin (also called 5-hydroxytryptamine, or 5HT) is similar to dopamine except it has a double ring structure in place of the single ring structure of dopamine. Serotonin is distributed widely in the brain, and appears to inhibit behaviour and activity often in a way that seem to balance the effects of norepinepherine. SSRIs are drugs that specifically inhibit the re-uptake of serotonin (making it increasingly available in the synapse). SSRIs have been found to be important drugs for the treatment of depression and obsessive compulsive disorder.

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